Cost & Insurance

Get the help you need, when you need it.

FINANCIAL SUPPORT

Understanding cost and coverage

What you pay for ZILBRYSQ can be affected by many different factors, and cost may vary depending on your insurance plan. Your out-of-pocket expense—what you pay for care that is not reimbursed by insurance, as well as any services not covered by insurance—may be affected by your:

Co-pay
Deductible
Out-of-pocket maximum
Co-insurance

Your out-of-pocket costs can also be affected by where you receive care and whether your doctor is in-network with your insurance provider.

UCB is committed to helping make ZILBRYSQ more affordable for you

Financial support options may be available to help you pay for your ZILBRYSQ prescription. UCB evaluates each request based on individual need.

With ONWARD™, enrolled patients will automatically be assessed at the individual level to understand their coverage and potential financial assistance options available (co-pay and PAP). If approved, their dedicated ONWARD Care Coordinator will help explain the program offering and what to expect.

Your ONWARD Care Coordinator can also get you up to speed on potential financial assistance options, which may include:

Savings on ZILBRYSQ

Based on eligibility, people who are commercially insured (such as coverage through your work or the healthcare marketplace; also called private insurance) may get help with out-of-pocket costs and pay as little as $0 for ZILBRYSQ.

The ZILBRYSQ Patient Assistance Program

Also based on eligibility, you may be able to receive ZILBRYSQ at no cost for up to 12 months.

Discover ONWARD™

Your ONWARD team can help you review potential financial assistance options for ZILBRYSQ.

ONWARD is provided as a service of UCB and is intended to support the appropriate use of UCB medicines. ONWARD may be amended or canceled at any time without notice. Some program and eligibility restrictions may apply.

EXPLORE HELPFUL RESOURCES

IMPORTANT SAFETY INFORMATION
INCLUDING BOXED WARNING

ZILBRYSQ is a medicine that affects part of your immune system. ZILBRYSQ may lower the ability of your immune system to fight certain infections. ZILBRYSQ increases your chance of getting serious and life-threatening meningococcal infections. You must complete meningococcal vaccines. Do not use ZILBRYSQ if you have a Neisseria meningitidis infection. ZILBRYSQ may also increase the risk of other types of serious infections. Pancreatitis and pancreatic cysts have happened in people who use ZILBRYSQ. The most common side effects of ZILBRYSQ include injection site reactions, upper respiratory tract infections, and diarrhea.

IMPORTANT SAFETY INFORMATION
INCLUDING BOXED WARNING

What is the most important information I should know about ZILBRYSQ?

ZILBRYSQ is a medicine that affects part of your immune system. ZILBRYSQ may lower the ability of your immune system to fight certain infections.

ZILBRYSQ increases your chance of getting serious and life-threatening meningococcal infections. Meningococcal infections may become life-threatening or fatal if not recognized and treated early.
- You must complete or update two types of meningococcal vaccines (for both serogroup B infections and serogroup A, C, W, and Y infections) at least 2 weeks before your first dose of ZILBRYSQ if you have not already had these vaccines.
- If your healthcare provider decided that urgent treatment with ZILBRYSQ is needed, you should receive meningococcal vaccination(s) as soon as possible.
- If you have not completed or updated vaccinations for meningococcal infections at least 2 weeks before your first ZILBRYSQ dose and ZILBRYSQ therapy must be started right away, you must also receive antibiotics.
- If you had a meningococcal vaccine in the past, you might need additional vaccination before starting ZILBRYSQ. Your healthcare provider will decide if you need additional meningococcal vaccination.
- Meningococcal vaccines do not prevent all meningococcal infections. Call your healthcare provider or get emergency medical care right away if you get any of these signs and symptoms of a meningococcal infection:
  - headache with nausea or vomiting
  - headache and fever
  - headache with a stiff neck or stiff back
  - fever
  - fever and a rash
  - confusion
  - muscle aches with flu-like symptoms
  - eyes sensitive to light

Your healthcare provider will give you a Patient Safety Card about the risk of meningococcal infection. Carry it with you at all times during treatment and for 2 months after your last ZILBRYSQ dose. Your risk of meningococcal infection may continue for several weeks after your last dose of ZILBRYSQ. It is important to show this card to any healthcare provider who treats you. This will help them diagnose and treat you quickly.

ZILBRYSQ is only available through a program called the ZILBRYSQ REMS. Before you can receive ZILBRYSQ, your healthcare provider must:

enroll in the ZILBRYSQ REMS.
counsel you about the risk of meningococcal infection.
give you the Patient Guide, including information about the signs and symptoms of meningococcal infection.
give you a Patient Safety Card about your risk of meningococcal infection, as discussed above.
make sure that you are vaccinated with two types of meningococcal vaccines and, if needed, get revaccinated with the meningococcal vaccines. Ask your healthcare provider if you are not sure if you need to be revaccinated.

ZILBRYSQ may also increase the risk of other types of serious infections.

ZILBRYSQ may increase your chance of getting Streptococcus pneumoniae and Haemophilus influenzae type b. Your healthcare provider will tell you if you should receive the Streptococcus pneumoniae and Haemophilus influenzae type b vaccinations.
Certain people may have an increased risk of gonorrhea infection. Talk to your healthcare provider about whether you are at risk for gonorrhea infection, about gonorrhea prevention, and about regular testing.

Call your healthcare provider right away if you have new signs or symptoms of infection.

Who should not use ZILBRYSQ?

Do not use ZILBRYSQ if you have a Neisseria meningitidis infection.

Before you use ZILBRYSQ, tell your healthcare provider about all of your medical conditions, including if you:

have an infection or fever.
are pregnant or plan to become pregnant. It is not known if ZILBRYSQ will harm your unborn baby.
are breastfeeding or plan to breastfeed. It is not known if ZILBRYSQ passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby if you use ZILBRYSQ.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

What are the possible side effects of ZILBRYSQ?

ZILBRYSQ may cause serious side effects, including:

See “What is the most important information I should know about ZILBRYSQ?”
Inflammation of the pancreas (pancreatitis) and other pancreatic problems. Pancreatitis and pancreatic cysts have happened in people who use ZILBRYSQ. Your healthcare provider will do blood tests to check your pancreas before you start treatment with ZILBRYSQ.
- Call your healthcare provider right away if you have pain in your stomach area (abdomen) that will not go away. Your healthcare provider will tell you if you should stop using ZILBRYSQ. The pain may be severe or felt going from your abdomen to your back. The pain may happen with or without vomiting. These may be symptoms of pancreatitis.

The most common side effects of ZILBRYSQ include:

injection site reactions.
upper respiratory tract infections.
diarrhea.

Tell your healthcare provider about any side effect that bothers you or that does not go away. These are not all the possible side effects of ZILBRYSQ. For more information, ask your healthcare provider or pharmacist. Call your doctor for medical advice about side effects. You may report side effects to FDA at www.fda.gov/medwatch or 1-800-FDA-10881-800-FDA-1088. You may also report side effects to UCB, Inc. by calling 1-844-599-CARE1-844-599-CARE [2273].

See the detailed Instructions for Use that comes with ZILBRYSQ for information on how to prepare and inject a dose of ZILBRYSQ, and how to properly throw away (dispose of) used ZILBRYSQ prefilled syringes.

INDICATION

What is ZILBRYSQ?

ZILBRYSQ is a prescription medicine used to treat adults with a disease called generalized myasthenia gravis (gMG) who are anti-acetylcholine receptor (AChR) antibody positive.
It is not known if ZILBRYSQ is safe and effective in children.

Please see the full Prescribing Information and Medication Guide for ZILBRYSQ, including the Boxed Warning regarding serious meningococcal infections. Please see the Instructions for Use for the ZILBRYSQ Single-Dose Prefilled Syringe. Talk to your healthcare provider about your condition or your treatment. For more information, go to www.ZILBRYSQ.com or call 1-844-599-22731-844-599-2273.