HOW TO USE ZILBRYSQ

What to know about injecting ZILBRYSQ

Starting a new treatment can bring a lot of questions. ZILBRYSQ has resources to help every step of the way. On this page, see how to inject as well as how to store and dispose of ZILBRYSQ syringes. As always, reach out to your healthcare provider with any questions you may have.

ZILBRYSQ syringe plungers in three different colors.

There are 3 different colors of syringe plunger based on dose. Your doctor will prescribe the correct dosage for you depending on your body weight.

ZILBRYSQ can be self-injected after proper training and preparation

Here’s what you need to know about getting started with self-injection

First, it’s important to follow the directions exactly as written. Starting with making sure to always use ZILBRYSQ as prescribed.

Second, you must discard the prefilled syringe after each use. Each prefilled syringe is for single use only. Do not reuse.

Third, you only take one dose of ZILBRYSQ per day at about the same time each day. Do not inject more than once each day.

If you miss a dose, inject a dose as soon as possible. Then, take your next dose at your regular scheduled time.

Choose a different site each time you give yourself an injection

  • If you want to use the same injection site, make sure it is at least 1 inch from the spot you used before
  • Do not inject ZILBRYSQ into an area that is red, tender, bruised, swollen, hard or that has scars or stretch marks
  • If injecting into the stomach (abdomen), do not inject within a 2-inch area around the belly button (navel)
  • Only inject into the back of the upper arm if the injection is being administered by a trained caregiver

For more information, review the Instructions for Use.

Your doctor is the best resource for you if you have any questions.

Step-by-Step ZILBRYSQ® Injection Guide.
Step-by-Step ZILBRYSQ® Injection Guide.

Step-by-Step Injection Guide

Learn more about injecting ZILBRYSQ at home or on the go.

ZILBRYSQ storage and disposal instructions

Storing ZILBRYSQ

  • Always store ZILBRYSQ in the original carton
  • You can store ZILBRYSQ one of two ways:
    • In a refrigerator between 36°F to 46°F (2°C to 8°C) until the expiration date on the carton. Do not freeze ZILBRYSQ*
    • At room temperature in the original carton for a single period of up to 3 months*
  • Do not place ZILBRYSQ back in the refrigerator after storing at room temperature
  • Do not use ZILBRYSQ if it has not been used within 3 months of storing at room temperature
  • Do not use ZILBRYSQ if the expiration date on the carton has passed or the carton seals have been broken

Disposing of your ZILBRYSQ Syringe

  • Throw away into an FDA-cleared sharps disposal container
    If you do not have an FDA-cleared sharps disposal container, you may use a household container that is:
    • Made of a heavy-duty plastic
    • Can be closed with a tight-fitting, puncture-resistant lid, without sharps being able to come out
    • Upright and stable during use
    • Leak-resistant
    • Properly labelled to warn of hazardous waste inside the container
  • Do not throw away the ZILBRYSQ syringe (prefilled or used) in your household trash

*Before injecting ZILBRYSQ, let the prefilled syringe warm up to room temperature (up to 86°F [30°C]), on a clean flat surface for 30 to 45 minutes. Do not warm the ZILBRYSQ prefilled syringe in any other way (for example in a microwave, in hot water, or in direct sunlight). Pharmacy prior to dispensing: Store ZILBRYSQ prefilled syringes refrigerated at 2°C to 8°C (36°F to 46°F) in the original carton until dispensing.
Keep ZILBRYSQ prefilled syringes and all medicines out of the reach of children.